• Current insulin user
  • Currently breastfeeding
  • Pregnant or planning to become pregnant within the next 6 months (Note: weight loss may cause previously lost fertility to return)
  • Have had bariatric surgery
  • Has one of the following comorbidities:
    • Active cancer
    • Heart attack or stroke within the last 6 months
    • Severe heart failure (grade 3 or 4)
    • Severe renal impairment (last eGFR <30 mls/min/1.73m²)
    • Active liver disease (excluding non-alcoholic fatty liver disease)
    • Active substance use disorder
    • Active eating disorder
    • Porphyria 
    • Untreated proliferative retinopathy (unless newly diagnosed and not yet screened)
  • Have had bariatric surgery
  • Health professional assessment that you are unable to understand or meet the demands of the NHS LCD Programme and/or monitoring requirements; or for whom the programme is not clinically appropriate; or for whom medication adjustment would not be appropriate